File:CoronavirusSizeFragment.jpg
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Summary
Coronaviruses lining the surface of a cell. Fragment of Figure 2(c) of publication at microbiologyresearch [1]
References
- ↑ https://www.microbiologyresearch.org/docserver/fulltext/jgv/12/2/JV0120020161.pdf?expires=1585289067&id=id&accname=guest&checksum=AD6D3235AB71E5FFD16BB8B4BBE32530 L.S.OSHIRO, J.H.SCHIEBLE AND E.I-I.LENNETTE. Electron Microscopic Studies of Coronavirus. J. gen. Virol. (1971), 12, 16I-I68 Printed in Great Britain. (Accepted I5 April I97I) Electron-microscopic studies of the morphology and development of a coronavirus (LINDER strain), isolated in human foetal diploid lung cells from a case of upper respiratory illness, revealed virus particles of diameter 80 to 16o nm. They were initially observed I2 hr after infection. Extracellular and intracytoplasmic virus concentration increased sharply at I8 hr and reached a maximum at 24 hr. The number of particles decreased slightly at 48 hr and by 72 hr many cells were lysed. The particles formed by budding into the cisternae of the endoplasmic reticulum or into an inclusion composed of tubular structures resembling part of the complete virus particle. There were cytoplasmic inclusions of dense particles within a granular matrix and surrounded by a double membrane. The release of particles by lysis is illustrated. Extracellular virus was specifically tagged with ferritin-labelled antibody.// .. p.164, Fig. 2. (a) Cytoplasmic inclusions composed of densely staining particles within a granular matrix and surrounded by a double membrane. (b) Numerous coronavirus particles on the cell surface and within the extracellular spaces. (c) Coronaviruses lining the surface of a cell. ..
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